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The government also plans to introduce a track-and-trace system for tobacco products to improve oversight of production and distribution and help combat the illegal tobacco trade

For example, if THC or HHC, which constantly interact with the CB1 receptor, are consumed regularly, they can disrupt the neuronal communication exerted by our endocannabinoids (7)

Indeed, although many studies have clearly shown that several interventions including pharmacological therapy and lifestyle modifications improve endothelial function under the condition of relatively mild vascular endothelial dysfunction [8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35], we have shown that advanced endothelial dysfunction is not reversible even by appropriate pharmacological therapy [94]

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