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aureus strains showed dose-dependent increases in biofilm formation, lower virulence, enhanced initial attachment, increased extracellular DNA release, and a higher autolysis rate, involving dysregulation of the accessory gene regulator (Agr) quorum-sensing system

However, things have started changing

[22] Most butane refill bottles come with an adapter, so before you try to refill, make sure the standard tip fits over the valve

Briefly, the stock solutions of NIC and DNC + NIC were diluted in physiological saline at the required concentration (0.5 mg/kg) for subcutaneous injection (s.c.) and adjusted to pH 7.27.4