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Although our finding that lymphocytes are not elevated in smokers contrasts with some recent reports 18,58 , our finding that granulocytes and monocytes are elevated in smokers is consistent with the literature 59

Early implementation reports describe these 'alternative-to-suspension' models as a way to maintain tobacco-free norms while providing support for quitting, although formal evaluations of their long-term effectiveness remain limited

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These findings further substantiate the therapeutic potential of PEO in the management of COPD