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But it had other medicinal uses as well: bites by poisonous snakes, spiders and insects were generally treated by cutting into the bite, sucking out the poison, and then rubbing [into the wound] with ground-up tobacco (presumably to act as an analgesic), followed by a careful diet (Ortiz de Montellano, quoting Sahagn)

ZYN is the most popular brand of nicotine pouches among non-combustible nicotine products that big tobacco has produced since the decline of cigarettes

Electronic supplementary material 12954_2006_73_MOESM1_ESM.doc (download DOC Additional File 1: Peer-Reviewed Scientific/Medical Articles Acknowledging that Smokeless Tobacco Use Confers Less Risk Than Cigarette Smoking, In Reverse Chronological Order 2006-1980

It contains the same addictive chemical, nicotine, contained in cigarettes