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This cell line may be more useful for studying substances that are active in their administered form, rather than for studying those that require biotransformation to reactive metabolites, because some cytochrome P-450 isoforms are not expressed in A549 cells (Castell et al

Research from the McCourt School of Public Policy at Georgetown University found that smokers report higher levels of chronic pain, use more opioid pain killers, report worse levels of mental health, and are more likely to have severe work limitations because of pain