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Evidence suggests that nicotine use during adolescence and young adulthood has long-term impacts on brain development, and tobacco use remains the leading cause of preventable death in the U.S., said Ohio Department of Health Director Amy Acton, MD, MPH

Without nicotine's enzyme induction, caffeine's effect doubles same cups of chai will produce twice the stimulant effect, potentially causing anxiety, insomnia, and jitteriness that mimic withdrawal and reduce quit success

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