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When UVR-induced DNA damage occurs before entry into the S phase, p53 halts the cell cycle at the G1 phase in part by transcriptionally inducing cyclin-dependent kinase inhibitor ( CDKN1A) , also known as p21 (WAF1/CIP1), a potent inhibitor of several cyclin-dependent kinase complexes

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This results in increased mobility, which you may notice when your teeth move around in their socket more than they should, and may even cause your teeth to fall out