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Description
FDA adds specificity by listing Harmful and Potentially Harmful Constituents (HPHCs), grouping chemicals into categories such as volatile organic compounds, carbonyls (e.g., formaldehyde), gases (e.g., carbon monoxide), metals, tobacco-specific nitrosamines (TSNAs), and polycyclic aromatic hydrocarbons (PAHs)

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Since the placenta has limited capacity to metabolize nicotine, this contributes to its higher levels in the fetal circulation compared to mothers [15]

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