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The additives gamma-heptalactone, gamma-valerolactone, gamma-decalactone, delta-decalactone, gamma-dodecalactone, delta-undecalactone and gamma-hexalactone are mild to weak inhibitors of CYP2A6, an enzyme within the P450 enzyme system, involved in the metabolism of nicotine (Juvonen et al
Oral Oncology, 49(4):314-321
Smokers are more likely to experience dry eye syndrome, a condition characterized by insufficient lubrication on the eye's surface
