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Although the conclusions were based on the results of a study involving mice, the researchers claim the results have implications for humans

Plastic inner frames, typically manufactured from injection-molded polypropylene (PP) or polyethylene terephthalate (PET), offer superior moisture barrier properties compared to standard paperboard, making them particularly relevant in markets with high ambient humidity conditions, such as Southeast Asia and tropical regions of Africa and Latin America

In summary, our analysis of PATH Study data from Wave 1 to Wave 5 partially supports the known harms of continued cigarette smoking among those with existing COPD and supports the known benefits of smoking cessation