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Mendelian randomization: coffee consumption to smoking heaviness In current smokers from UK Biobank ( N = 10 665) and CGPS ( N = 14 929), each coffee consumption-increasing allele of the genetic risk score was associated with consuming 0.09 additional cups of coffee per day (95% CI: 0.07, 0.12) (Supplementary Table S23, available as Supplementary data at IJE online)

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While Kilmer does feature in the new film reprising his iconic role, the concern around his speaking voice loomed large for the audience

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