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Assessment between the presence/absence of investigated features and selected dichotomous variables, i.e., age at last examination 30%) mucocutaneous features were piezogenic papules of the heels (86.7%), light blue sclerae (58.7%), uvular abnormalities (44.1%), acquired cutis laxa/premature skin aging (41.3%), striae distensae/rubrae (40%), and keratosis pilaris/hyperkeratosis of extensor surfaces (30.7%)

The statistical model to generate these estimates is updated to reflect changes in the marketplace and is the centerpiece of our empirical analysis
