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Sustained delivery: Vaping provides steadier nicotine levels over 30-60 minutes versus cigarettes' sharp spike-and-crash pattern
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Nicotine and cotinine can be detected through: Urine tests (most common) Blood tests Saliva tests Hair tests Urine testing is the most widely used method for employment and insurance screening

Reduced nicotine cigarettes: smoking behavior and biomarkers of exposure among smokers not intending to quit
