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At its base, it is radical nihilism, the denial of meaning to existence

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However, some people, especially those with a history of mental illness, may experience serious adverse side effects, such as: Changes in mood including depression and mania Hallucinations and delusions Paranoia Thoughts of homicide and/or suicide Aggression and hostility Anxiety and panic Skin redness, swelling, and peeling If you experience any of these symptoms, stop taking Chantix immediately and see your doctor