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The rescue effects of these agonists were specifically reversed by their corresponding inhibitors, SKF96365, HC067047, GsMTx-4 and Pyr3, further supporting the involvement of these channels in mediating the Ca 2+ signal downstream of XKR8 (Fig

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A meta-analysis has demonstrated that studies in adults which used higher doses of prednisolone (1 mg/kg/day, maximum 60 mg) have a higher remission rate and also have more steroid-related side effects than those which used a lower dose (0.5 mg/kg/day)