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H., Kostyniak P

& Hammond, R

Of particular importance, sufficient time must elapse before initiating TCA treatment in a patient being withdrawn from fluoxetine, given the long half-life of the parent and active metabolite (at least 5 weeks may be necessary)

While large-scale randomized trials in MCAS are limited, case-report literature describes improvement in patients with overlapping conditions such as MCAS and severe postural orthostatic tachycardia syndrome (POTS) when naltrexone was included as part of a comprehensive care plan
