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6a, when pristine PPS was employed, the accumulated Hg 0 adsorption efficiency was 12.1% within 120 min

In addition to inhibiting Notch3, a combined treatment with TMZ plus CHAC1 stimulated ROS generation, increased intracellular Ca 2+ levels, and led to the loss of MMP [221]

Research in PD animal models has shown that NPT200-11 reduces abnormal -syn accumulation, suppresses astrocytic activationthus attenuating neuroinflammationand normalizes striatal dopamine transporter (DAT) levels, alleviating motor deficits in PD mice [155]

Factors such as access to healthcare, early diagnosis, and lifestyle also influence disease progression, making thalassemia a highly variable condition in clinical practice [10][3]