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Description
Together, these findings identify EAR-20 as a novel subunit-dependent positive allosteric modulator with the potential to inspire the development of small molecules targeting the same binding site, offering proof of concept for therapeutic strategies to treat neurological and neurodevelopmental disorders
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The search was limited to articles published in English, with a focus on recent studies (20102024) while including seminal older works for historical context
10.1016/j.cell.2017.09.021 126 SucherE.SucherR.GradistanacT.BrandacherG.SchneebergerS.BergT
