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The high (millimolar) concentration of the reduced form highlights its central role in the control of those processes (58)
Elevated ROS levels induce macrophages to polarize toward the M1 phenotype, thereby augmenting the release of inflammatory cytokines and promoting a pro-inflammatory role (150)
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[DOI] [PubMed] [Google Scholar] 214.Williams BB, Van Benschoten AH, Cimermancic P, Donia MS, Zimmermann M, Taketani M, et al
