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doi: 10.1111/jnc.13347

Single-cell RNA-seq unravels alterations of the human spermatogonial stem cell compartment in patients with impaired spermatogenesis

Taken together, the pattern suggests that a controlled, short-lived immune activation may accompany epithelial repair, consistent with the accelerated wound closure observed in HCEpiC assays under basal, inflammatory and oxidative stress conditions ( Importantly, the interpretation of increased Th1-associated cytokines as part of a repair-associated response rather than purely deleterious inflammation is supported by emerging evidence on corneal wound healing biology (Wilson, 2020)