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In summary, the acetyl-L-carnitine group scored better when assessing patient function using the modified Rankin Scale (mRS) and National Institutes of Health Stroke Scale (NIHSS) score, and supplementation caused a significant decline in the serum levels of TNF- , ICAM-1, IL-6, and NSE and a significant increase in the serum level of superoxide dismutase (SOD), TAC, GPx, and total L-carnitine in the subjects with acute ischemic stroke compared to the placebo treatment

Clinical trials are investigating the effects of PGC-1 modulation in various diseases, which is crucial for determining the safety and efficacy of potential therapies targeting PGC-1

This NO-producing capability forms the foundation for most of L-arginine's purported benefits

In some cases, neuropathy occurs as a side effect of chemotherapy