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Subsequently, DP breaks cysteinyl glycine into cysteine and glycine, which are reabsorbed into the cell to engage in a novel GSH synthesis pathway (summarized in Fig
For other products, long-term exposure to cold temperatures can shorten the products lifespan, negatively impact stability and affect performance
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ROS promotes receptor interacting serine/threonine kinase 3 (RIP3) phosphorylation, which subsequently triggers downstream mixed lineage kinase domain-like pseudokinase (MLKL) phosphorylation and activates MLKL translocation to the plasma membrane, increasing membrane permeability and inducing necrotic death in HCC tumor cells [125]
