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methylcobalamin and 5-deoxyadenosylcobalamin are metabolically active forms [24,25,26]

H.StahlE.ErdmanR.GatalicaZ.et al (2015)

The clinical signs and symptoms of cobalamin-related remethylation disorders may vary considerably and affect multiple organ systems, most prominently the nervous system and the bone marrow

I had 2 glasses The joys Hi again Charlwobble It is not uncommon for some symptoms to appear to get worse before they get better as the B12 you are having starts repairing the damage done to your nervous system and your brain starts getting multiple messages from part of the body it had "forgotten about" or lost contact with