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doi: 10.3390/nu14112253

Choline detoxifies amines, which are the by-products of protein metabolism

While speculative, early research suggests microbiome composition influences metabolic health outcomes independently and may be modifiable to improve treatment response

Researchers studying metabolic dysfunction in adipose tissue have identified NNMT as one of the most consistently upregulated enzymes in obese white fat, making it a high-confidence therapeutic target for metabolic intervention