most abundant glutathione transferase in liver alpha 1 2 3 Frontiers Glutathione Transferase Alpha - an
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doi: 10.1007/s12020-014-0336-5
Describe the role of NADPH in detoxifying reactive oxygen species, and explain which cell types depend the most on the pentose phosphate pathway
The nuclear transcription factor NEF2 serves as an inducer of SLC7A11 expression, while tumor suppressor genes TP53, BAP1, and BECN1 downregulate SLC7A11 expression [40,41,42]
Specifically, rapamycin binds to FKBP12, forming a complex that inhibits mTORC1 activity
