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Description
Mechanistically, myeloid-specific NAMPT deletion impairs M2 polarization by destabilizing HIF-1 and reducing efferocytosis
113 CDC37, a kinase-specific co-chaperone, binds the HSP90 NTD and inhibits ATPase activity while tethering kinase clients, maintaining HSP90 in an open conformation until proper timing for activation is reached
F.WeiY.et al (2013)
Still, metabolomics studies of DR effects have been very limited
