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The activity of these reabsorption proteins depends essentially on the gene expression of certain regions of the DNA

doi: 10.1038/jid.2010.433

The more recent STEP UP trial tested a higher dose of 7.2 mg and showed average weight loss of 20.7% at 72 weeks

[80], for a better classification of the disease (e.g., MCT grade 3 according to Patnaik and high-grade according to Kiupel)
