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Nevertheless, the innate immune system also displays trained immunity, whereby innate immune cells such as macrophages, monocytes, and natural killer cells acquire immunological memory and enhance responsiveness of cells when they reencounter unrelated pathogens 20

In addition to these common types of autophagy, there are also selective autophagy forms with specific substrate degradation, including mitochondrial autophagy, lipid droplet autophagy, aggregate autophagy, endoplasmic reticulum autophagy, and ribosomal autophagy (Ma et al., 2024)

On November 4, 2021, Molnupiravir became the first oral antiviral drug approved in the UK to treat COVID-19 patients

Cairns CJ, Robertson J