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In the pivotal SURMOUNT-1 clinical trial, participants taking the highest dose of tirzepatide achieved an average body weight reduction of up to 22.5% over 72 weeks
The GH/IGF-1 axis in obesity: physiological and pathological aspects
The FDA restricted many peptides in 2023, and HHS signaled a partial reversal in early 2026, but nothing is fully settled
Studies have explored how this compound interacts with copper-dependent enzymes including lysyl oxidase, which plays a critical role in collagen and elastin crosslinking
