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In: Presented at 52nd Annual Meeting of the European Association for the Study of Diabetes

In the absence of myelin, redistribution of Na + occurs to maintain the transmission of nerve impulses that increases energy demand, and this produces a situation of virtual hypoxia. At the end, the demand exceeds the capacity of axonal mitochondria to produce enough ATP, which causes an increase in the concentration of Ca 2+ in the axon

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With the objective of investigating the effects on longitudinal bone growth rate (LGR), body weight (BW), and GH release, ipamorelin in different doses (0, 18, 90, and 450 microg/day) was injected s.c