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Description
Activation of the DDR in specific tissues could influence the function of vital metabolic organs, thereby provoking systemic insulin resistance
PPAR is highly expressed in the liver and plays a key role in regulating the first step of sphingolipid biosynthesis via SPT
doi: 10.1038/s41380-019-0477-2 64 WangL.LeonardsC

Rabinowitz, and Markus Ralser
