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Abstract Providing NO-system importance, we suggest that one single application of the NOS-blocker L-NAME may induce retinal ischemia in rats, and that the stable pentadecapeptide BPC 157 may be the therapy, since it may interact with the NO-system and may counteract various adverse effects of L-NAME application

Target the human alanine/serine/cysteine transporter 2(asct2): achievement and future for novel cancer therapy

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3.3 Anticancer mechanisms of omega-3 fatty acids 3.3.1 Regulation of inflammatory pathways Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) reduce the levels of pro-inflammatory cytokines and downregulate inflammatory mediators such as COX-2, TNF-, NF-B, and prostaglandin E2 (PGE 2 ), which attenuates cancer-related inflammatory responses (50, 51)