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An untreated vitamin B12 deficiency can lead to neurological problems or pernicious anemia, which occurs when your body doesnt have enough B12 to produce the amount of red blood cells it needs ( Vitamin B12 shots are typically the most common way to prevent or treat a deficiency

In addition to inhibiting NF-B, riboflavin inhibits the release and expression of High-mobility group protein B1, a nuclear factor involved in sepsis regulation and other immune-mediated conditions with a critical role in sepsis-associated multiple organ failure (60)
doi: 10.1038/nature08890 131 IovinoMAgathouSGonzlez-RuedaADel Castillo Velasco-HerreraMBorroniBAlbericiAet al