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Preclinical studies investigating isolation-induced psychopathology suggest that these affective changes may involve endocannabinoid system dysregulation in limbic and cortical regions highlighting the potential therapeutic value of modulating endocannabinoid tone ( Consistent with previous reports ( This study was conducted exclusively on male mice as a pilot experiment to characterize preliminary neurobehavioral outcomes before expanding the investigation to both sexes

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[DOI] [PMC free article] [PubMed] [Google Scholar] 187.Shahnawaz M., Mukherjee A., Pritzkow S., Mendez N., Rabadia P., Liu X., Hu B., Schmeichel A., Singer W., Wu G., et al

But green tea extract is safe for most people, inexpensive, and may provide complementary benefits including antioxidant protection that supports overall metabolic health
