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54 Both pharmacologic 11-HSD1 inhibition and genetic knockout of 11-HSD1 lead to increased expression of brown adipose tissuespecific genes, whereas overexpression of 11-HSD1 in mice leads to decreased expression of these genes in brown adipose tissue

ENZ treatment significantly increased LipROS levels, an effect reversed by LTF knockdown, indicating that LTF is a crucial mediator of ENZ-induced ferroptosis (Fig

Spinal injections to treat back pain are typically safe

eLife 3:125
