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burgdorferi , like many bacteria, can form persister organisms either under antibiotic pressure or during stationary phase growth, and that these persister organisms are antibiotic-tolerant and are less likely to be killed with standard antibiotics (137, 138)

No established upper limit exists because excess b12 excretes through kidneys without causing harm
Activated microglia, the immune cells of the brain, release inflammatory mediators that sensitize pain pathways

Int J Mol Med, 2003
