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The cGAS/STING pathway plays a key role in the chronic inflammatory network by activating NF-B and NLRP3 to promote the production of multiple inflammatory factors (162)

[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Paramanya A., Ali A

These pathways drive DAMP secretion, remodeling the TIME and modulating tumor immune interactions [5,6,7]
