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Notably, BBB dysfunction does not occur uniformly across the brain: the hippocampus and certain cortical regions exhibit an early and more severe BBB breakdown in patients with AD [102]

Vitamin B12 is necessary for patients with a low serum level of vitamin B12 because they take particular medications or because they suffer from pernicious anemia, gastrointestinal or autoimmune disorders, or alcoholism
The extract of Salvia officinalis can significantly reduce insulin levels and the homeostasis model assessment of insulin resistance in PCOS patients, and significantly increase the quantitative insulin sensitivity check index, thus improving insulin resistance markers (64)

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