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Exercise-induced IL-6, mainly from skeletal muscle, may inhibit pro-inflammatory cytokines like TNF and IL-1 and stimulate anti-inflammatory mediators

The SMASH score, including synovitis, cartilage destruction, and bone erosion, was analyzed according to a previous article 48

This decreases the darker eumelanin and increases the lighter pheomelanin, leading to a lighter and fairer skin tone

PloS One (2013) 8(8):e71272
