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Description
Once activated, caspase-3 initiates the cleavage of a downstream substrate, such as nuclear poly (ADP-ribose) polymerase (PARP), which facilitates cellular disassembly and serves as a biomarker of cell apoptosis
The multiple GSH functions will be described, as well as the importance of GSH compartmentalization into distinct subcellular pools and inter-organ transfer
10.1038/nature16187 12 GuptaS
Reconstitution & Handling Guidelines Because of the highly concentrated peptide mass (80mg) and the inclusion of the copper ion complex, reconstitution must be handled methodically to avoid shearing the peptide bonds: Recommended Solvent: Bacteriostatic Reconstitution Solution (0.9% Benzyl Alcohol)
