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Although the overall incidence is estimated at 1/5000 to 1/50,000, the occurrence of fatal hepatotoxicity could be as high as 1/800 to 1/500 in these high-risk groups [11]

The TMEM106B-cathespin D interaction may be important for maintaining proper cathepsin D levels [132]

Cell Factories 20 , 211 (2021)
