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Nat Rev Neurosci 2007

The brain's high metabolic demands and vulnerability to oxidative stress make glutathione particularly crucial for maintaining healthy neurological function, and the enhanced bioavailability of this modified form supports superior cellular protection compared to traditional glutathione supplementation [5]

IGF1R regulates the expression of ASS1 and PYCR1 by related signaling pathwayscMYC axis To further explore the mechanism by which IGF1R regulates ASS1 and PYCR1 expression, we first inhibited the expression of IGF1R and found that ASS1/PYCR1 was downregulated in vivo (Supplementary Fig
