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does msm raise glutathione levels Biological functions of methylsulfonylmethane and its application in animal production: a review Protective Effect of Methyl Sulfonyl
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10.1038/nchembio821 137 ZhengH.XiaoW

This conjugation effectively wraps the toxin, neutralizing its harmful effects and transforming it into a water-soluble compound that can be safely excreted form the body through the GI tract, urine, or sweat

Huang, D., Ou, B., & Prior, R

Kojic acid works faster on stubborn dark spots but can irritate sensitive skin
