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However, the mechanistic rationale for combining these agents is sound and warrants further investigation

Bennett DJ, Gorassini M, Fouad K, Sanelli L, Han Y, Cheng J

CD38-specific sdAbs, such as sdAb 2F8, characterized by our laboratory, showing excellent tumor targeting and their engineered constructs, such as biparatopic antibodies and chimeric antibodies, represent a new generation of theranostic agents for diagnosis and treatment CD38-expressing malignancies

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