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Dendritic cells in COVID-19 Immunopathogenesis: insights for a possible role in determining disease outcome

In contrast, its intestinal microbial metabolite, urolithin, possesses better biological activity and higher bioavailability [173]

The prooxidant oxidative stress imbalance needs an antioxidant system able to balance it and the principal role in antioxidant defense is carried out by antioxidant enzymes, with the paramount involvement of small-molecule antioxidant compounds like GSH

The increased H 2 O 2 produces OH, which possesses the highest reactivity and the strongest oxidizing power among ROS, via the Fenton reaction (Figure 2)