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Description
Statistical analysis and graphical representations were performed using GraphPad Prism, version 8 (GraphPad Software Inc., San Diego, California, USA), using a one-way analysis of variance (ANOVA), followed by a Tukeys test to determine the statistical significance between various groups

Permeation techniques: Microneedles and topical permeation enhancers have been studied to increase delivery, though translation to routine cosmetic use requires safety and regulatory evaluation (PubMed

doi: 10.1055/s-2007-979231

Niacinamide has been studied for its effects on skin barrier function
