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This, in turn, increases the potential for an embolic event to occur [4]
The Japanese Kampo medicine Yokukansan prevents delirium following major cancer surgery in elderly patients by regulating plasma phospholipid metabolism, with its mechanism of alleviating cerebral oxidative stress validated in animal models [300]

However, when chronically exposed to elevated MGO, astrocytes might reduce their detoxification properties leading to overall damage to the cell and its environment
