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In summary, copper is essential for thyroid hormone metabolism, oxidative balance, and endocrine health

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( C ) GO term analysis showing the biological processes enriched in the -1 subcluster

Moreover, supplementation with Lactobacillus plantarum (DP189) and GOS restored gut microbial composition, improved gut and BBB integrity, reduced cortical inflammation and elevated acetylcholinesterase activity, reversing anxiety and depression-like behaviors in mice (Wang J
