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Expanding the coverage of regulons from high-confidence prior knowledge for accurate estimation of transcription factor activities

Biochemistry 2004;43:8429-8438

Likewise, experimental study illustrated that expression of ePRL in the macrophages and monocytes are activated by adrenergic pathways with subsequent polarization of macrophages toward the inflammatory one (M1) [31]

This stage of research is crucial for understanding the efficacy and safety of these inhibitors before they can be considered for clinical use
