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Description
Atropine readily crosses the placental barrier and enters the fetal circulation

however, Compounds 1.62 and 1.64 , both with changes in D-cysteine stereochemistry, showed a loss of activity with GPx or GR

In cancer, CDO has been shown to divert the flow of cysteine away from glutathione synthesis, thereby promoting the production of ROS

Nrf1 and c-Jun binds to both sites while Nrf2 binds only to the distal NFE2 site
